NIOSH has conducted research looking at the effects of shift work. Here are links to NIOSH webpages that should provide a lot of good information:

Click here for Shiftwork: A Guide for Schedule Design

Click here for Work Schedules: Shift Work and Long Hours

Click here for the NIOSH Total Worker Health page, it also has links to shift work, sleep and fatigue and a link to resources on substance abuse.

Hope this info helps.

Thanks for the share, MB!